Cutoff levels for newborn screening of 21-OH deficiency in a Brazilian metropolitan area
The proposed 17OHP cutoff strategy effectively reduced false positives, improving specificity, LR+, PPV, and accuracy Thus, it optimized CAHNBS programs while minimizing unnecessary costs and parental distress.
Authors
- Fábio Ferreira Amorim (ORCID: https://orcid.org/0000-0003-0929-5733)
- Sérgio Eduardo Soares Fernandes (ORCID: https://orcid.org/0000-0002-2511-400X)
- Cláudia Vicari Bolognani (ORCID: https://orcid.org/0000-0003-1521-475X)
- Kallianna Paula Duarte Gameleira
- Juliana de Vasconcellos Thomas (ORCID: https://orcid.org/0000-0001-9185-7998)
- Vitor Guilherme Brito de Araújo
Institutions
- Governo do Distrito Federal (BR)
- Secretaria de Estado de Educação do Distrito Federal (BR)
- Escola Superior de Ciências da Saúde (BR)
Publication Details
- Journal
- Jornal de Pediatria
- Published
- 2025-04-21
- DOI
- https://doi.org/10.1016/j.jped.2025.03.003
- Primary Topic
- Sexual Differentiation and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00