Methotrexate-related drug reactions on kidneys and liver in rheumatoid arthritis: an analysis of spontaneous reports in EudraVigilance
Liver dysfunction was reported nearly three times more often than renal impairment. However, the kidneys need to be especially watched for, since a fatal outcome was considerably more common in renal failure. More precise and standardized recommendations on renal function tests might be necessary to support physicians in the complex treatment of RA.
Authors
- Kathrin Jobski (ORCID: https://orcid.org/0000-0002-3957-9721)
- Falk Hoffmann (ORCID: https://orcid.org/0000-0003-0182-5373)
- Carsten Bantel (ORCID: https://orcid.org/0000-0002-1165-8081)
- Kai Khoroshun
Institutions
- Carl von Ossietzky Universität Oldenburg (DE)
- Klinikum Oldenburg (DE)
Publication Details
- Journal
- Arthritis Research & Therapy
- Published
- 2025-04-05
- DOI
- https://doi.org/10.1186/s13075-025-03551-6
- Citations
- 6
- Primary Topic
- Rheumatoid Arthritis Research and Therapies
- Type
- article
- Field-Weighted Citation Impact
- 10.01
Funders
- Carl von Ossietzky Universität Oldenburg