Motion-unrestricted dynamic electrocardiogram system utilizing imperceptible electronics
Electrocardiogram (ECG) plays a vital role in the prevention, diagnosis, and prognosis of cardiovascular diseases (CVDs). However, the lack of a user-friendly and accurate long-term dynamic electrocardiogram (DCG) device in motion has made it challenging to perform many daily cardiovascular risk screenings and assessments, such as sudden cardiac arrest, resulting in additional economic burdens on society. Here, we present a motion-unrestricted dynamic electrocardiogram (MU-DCG) system, which employs skin-conformal, imperceptible electronics for long-term, comfortable, and accurate 12-lead DCG monitoring. To facilitate assembly for use on the skin, the MU-DCG system features a pressure-activated flexible skin socket for stably soft-connecting the on-skin soft module and the off-skin stiff module during dynamic movements. Crucially, blinded cardiologist evaluations confirm minimal motion artifacts in MU-DCG-acquired ECG signals. Our results demonstrate that the MU-DCG system, with large-area, ultra-thin on-skin electrodes/leads, and an off-skin module, accomplishes anti-motion interference acquisition and in-situ analysis while retaining wearing imperceptibility.
Authors
- Wancheng Shao
- Zigan Xu
- Lu‐Qi Tao (ORCID: https://orcid.org/0000-0003-2653-2868)
- Tian‐Ling Ren (ORCID: https://orcid.org/0000-0002-7330-0544)
- Zhongwei Cheng (ORCID: https://orcid.org/0000-0002-7110-4101)
- Ziyi Xie (ORCID: https://orcid.org/0000-0002-9004-225X)
- Tianrui Cui (ORCID: https://orcid.org/0000-0003-2425-5924)
- Xiao Liu (ORCID: https://orcid.org/0000-0002-5570-289X)
- Ding Li (ORCID: https://orcid.org/0000-0002-5552-3920)
- Jiahao Liu (ORCID: https://orcid.org/0000-0001-6890-9147)
- Xin Li (ORCID: https://orcid.org/0000-0002-4370-2876)
- Xu Wang (ORCID: https://orcid.org/0009-0000-0655-2509)
- Jun Zhou (ORCID: https://orcid.org/0000-0003-2098-9621)
- Xiaoming Wu (ORCID: https://orcid.org/0000-0002-6411-1717)
- Houfang Liu (ORCID: https://orcid.org/0000-0002-3941-8936)
- Zhikang Chen (ORCID: https://orcid.org/0009-0003-2568-6184)
- Shuwei Xu (ORCID: https://orcid.org/0000-0001-8696-8028)
- Jinming Jian
- Zirui Dong
- Yi Yang
Institutions
- University of Electronic Science and Technology of China (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- Tsinghua University (CN)
Publication Details
- Journal
- Nature Communications
- Published
- 2025-04-05
- DOI
- https://doi.org/10.1038/s41467-025-58390-5
- Citations
- 18
- Primary Topic
- EEG and Brain-Computer Interfaces
- Type
- article
- Field-Weighted Citation Impact
- 25.76
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Tsinghua University
- National Key Research and Development Program of China