Pregnancy Rates After Frozen Embryo Transfer: Insights from an Indian Government Hospital

Objective: This study aims to evaluate the outcomes of frozen embryo transfer (FET) cycles performed at the Department of Reproductive Medicine and Surgery, SAT Hospital, Government Medical College Trivandrum Methods: A prospective observational study was conducted involving 190 FET cycles in 170 subjects. Demographic and clinical data, including age, body mass index (BMI), duration of infertility, ovarian reserve (assessed by Antral Follicle Count and Anti-Müllerian Hormone), stimulation protocol, and endometrial preparation were analysed. The clinical outcomes, including clinical pregnancy rate, implantation rate, miscarriage rate, and multiple pregnancy rate, were recorded. Results: The study found a clinical pregnancy rate (CPR) of 35.7% per transfer cycle and 40% per subject. The implantation rate was 22.8% per transferred embryo, while the miscarriage rate was 5.2% per cycle. The ongoing pregnancy rate was 30.5%, with multiple pregnancies occurring in 9.5% of cycles. Conclusion: The outcomes of FET cycles at SAT Hospital are comparable to European averages, with a favourable CPR and implantation rate. Key areas for improvement include embryo culture till blastocyst formation and the implementation of an elective single embryo transfer (eSET) policy to reduce multiple pregnancy risks. Continuous evaluation and evidence-based advancements shall optimise ART success at SAT Hospital, reinforcing its role in reproductive medicine in South India.