Functional outcomes reporting using an adjusted outcomes index for mechanical thrombectomy in anterior cerebral artery occlusions – A case series

• Stent-retrievers with luminal diameter range 3–6 mm are optimal for ACA MT. • The 90-day mRS score may not accurately reflect functional outcomes for ACA MT. • Baseline-adjusted NIHSS with ≥41 % score decrease may challenge utility of 90-day mRS. The decision to intervene with mechanical thrombectomy (MT) for anterior cerebral artery (ACA) strokes is often made based on anticipated long-term functional outcomes using modified Rankin scores (mRS) which is primarily based on ambulatory status. Here, we review our single-center experience with ACA MT and evaluate the utility of various functional outcomes reporting. A case series of 15 patients undergone MT for ACA stroke using the Solitaire or Trevo stent-retrievers was completed. The data retrieved included patient demographics, initial National Institute of Health Stroke Scale (NIHSS), thrombolysis in cerebral infarction (TICI) scores and number of passes, post-procedure 24-hour NIHSS, intra-operative or post-operative complications, discharge NIHSS and mRS, and 90-day mRS. There were 87 % favorable ACA TICI scores (i.e. 2B/C and 3) and 80 % first pass recanalization rate. The Solitaire 4 mm stent-retriever was employed in the majority of cases (60 %). No procedural complications were noted in 73 % of cases and no hemorrhagic conversion in 87 % of cases. 90-day mRS scores of 0–2 were noted in 26 % of patients. Using an adjusted outcomes index, 80 % of patients had favorable outcomes based on the 24-hour baseline-adjusted NIHSS score decrease of ≥41 %. Our preliminary findings here highlight successful radiographic and favorable functional outcomes using the Solitaire and Trevo stent-retrievers (3–6 mm luminal diameter) for ACA MT when reporting with the adjusted outcomes index as compared to the 90-day mRS score. Further studies comparing these outcomes reporting metrics with a larger sample size will be needed to further elucidate this notable difference.

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Journal
Interdisciplinary Neurosurgery
Published
2025-04-05
DOI
https://doi.org/10.1016/j.inat.2025.102021
Primary Topic
Acute Ischemic Stroke Management
Type
article
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article

Functional outcomes reporting using an adjusted outcomes index for mechanical thrombectomy in anterior cerebral artery occlusions – A case series

Alex Chebl, Giulia Santangelo, Praveen Sanmugananthan, Michael Fana et al.
Interdisciplinary Neurosurgery
Acute Ischemic Stroke Management
article

Functional outcomes reporting using an adjusted outcomes index for mechanical thrombectomy in anterior cerebral artery occlusions – A case series

Alex Chebl, Giulia Santangelo, Praveen Sanmugananthan, Michael Fana, Max Kole, Horia Marin
article en

Abstract

• Stent-retrievers with luminal diameter range 3–6 mm are optimal for ACA MT. • The 90-day mRS score may not accurately reflect functional outcomes for ACA MT. • Baseline-adjusted NIHSS with ≥41 % score decrease may challenge utility of 90-day mRS. The decision to intervene with mechanical thrombectomy (MT) for anterior cerebral artery (ACA) strokes is often made based on anticipated long-term functional outcomes using modified Rankin scores (mRS) which is primarily based on ambulatory status. Here, we review our single-center experience with ACA MT and evaluate the utility of various functional outcomes reporting. A case series of 15 patients undergone MT for ACA stroke using the Solitaire or Trevo stent-retrievers was completed. The data retrieved included patient demographics, initial National Institute of Health Stroke Scale (NIHSS), thrombolysis in cerebral infarction (TICI) scores and number of passes, post-procedure 24-hour NIHSS, intra-operative or post-operative complications, discharge NIHSS and mRS, and 90-day mRS. There were 87 % favorable ACA TICI scores (i.e. 2B/C and 3) and 80 % first pass recanalization rate. The Solitaire 4 mm stent-retriever was employed in the majority of cases (60 %). No procedural complications were noted in 73 % of cases and no hemorrhagic conversion in 87 % of cases. 90-day mRS scores of 0–2 were noted in 26 % of patients. Using an adjusted outcomes index, 80 % of patients had favorable outcomes based on the 24-hour baseline-adjusted NIHSS score decrease of ≥41 %. Our preliminary findings here highlight successful radiographic and favorable functional outcomes using the Solitaire and Trevo stent-retrievers (3–6 mm luminal diameter) for ACA MT when reporting with the adjusted outcomes index as compared to the 90-day mRS score. Further studies comparing these outcomes reporting metrics with a larger sample size will be needed to further elucidate this notable difference.

Interdisciplinary NeurosurgeryVol. 40
Henry Ford Health System (US), Kansas City University (US), Wayne State University (US)
Openalex Percentile: Top 90%
Acute Ischemic Stroke Management
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