Pseudo-orthostatic tremor in a cat

An 11-month-old male castrated shorthaired cat was presented with a tremor in both pelvic limbs, which only occurred when standing (ie, countering gravity) or during active extension of the stifle. General clinical and neurological examinations were normal aside from the tremor of the pelvic limbs, which disappeared on performing a weight-bearing lifting test. Needle electromyography of both pelvic limbs in the conscious state confirmed a low-frequency (6 Hz) tremor. The cat was diagnosed with pseudo-orthostatic tremor. The tremor amplitude waxed and waned over time. The cat remained ambulatory and playful, but often assumed lateral recumbency and seemed to have difficulty jumping. Treatment with gabapentin (10-20 mg/kg PO q8h) for 3 weeks followed by clonazepam (0.1 mg/kg PO q12h) for 1 day (with unacceptable adverse effects) did not result in improvement.

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Publication Details

Journal
Journal of Veterinary Internal Medicine
Published
2025-04-05
DOI
https://doi.org/10.1111/jvim.17290
Primary Topic
Neurological disorders and treatments
Type
article
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article

Pseudo-orthostatic tremor in a cat

Laurent Garosi, Mark Lowrie, Koen M. Santifort, Marende M. de Gier et al.
Journal of Veterinary Internal Medicine
Neurological disorders and treatments
article

Pseudo-orthostatic tremor in a cat

Laurent Garosi, Mark Lowrie, Koen M. Santifort, Marende M. de Gier, Dian Schuil
article en

Abstract

An 11-month-old male castrated shorthaired cat was presented with a tremor in both pelvic limbs, which only occurred when standing (ie, countering gravity) or during active extension of the stifle. General clinical and neurological examinations were normal aside from the tremor of the pelvic limbs, which disappeared on performing a weight-bearing lifting test. Needle electromyography of both pelvic limbs in the conscious state confirmed a low-frequency (6 Hz) tremor. The cat was diagnosed with pseudo-orthostatic tremor. The tremor amplitude waxed and waned over time. The cat remained ambulatory and playful, but often assumed lateral recumbency and seemed to have difficulty jumping. Treatment with gabapentin (10-20 mg/kg PO q8h) for 3 weeks followed by clonazepam (0.1 mg/kg PO q12h) for 1 day (with unacceptable adverse effects) did not result in improvement.

Journal of Veterinary Internal MedicineVol. 39(3)
Oracle (United States) (US), Preston University (US), Oracle (United Kingdom) (GB), Zel Technologies (United States) (US), Rijnstate Hospital (NL), GGD Hart voor Brabant (NL)
Openalex Percentile: Top 89%
Neurological disorders and treatments
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Pseudo-orthostatic tremor in a cat — Laurent Garosi, Mark Lowrie, et al. · Journal of Veterinary Internal Medicine (2025) | TGRS Research Map | TGRS