Intraoperative brain tumor classification via laser-induced fluorescence spectroscopy and machine learning
This initial ex vivo clinical study demonstrated the ability of TumorID to rapidly differentiate and classify various pathologies and surrounding brain in a configuration that can be easily translated to scan in vivo. This classification power could allow TumorID to augment surgical decision-making by enabling rapid intraoperative tissue diagnostics and border delineation, potentially improving patient outcomes by allowing for a more informed and complete resection.
Authors
- Syed M. Adil (ORCID: https://orcid.org/0000-0002-2322-5478)
- William C. Eward (ORCID: https://orcid.org/0000-0002-4553-1943)
- Thomas J. Cummings
- Jacob Sperber (ORCID: https://orcid.org/0000-0001-6290-7300)
- Sully F. Chen (ORCID: https://orcid.org/0000-0001-7719-469X)
- Peter E. Fecci (ORCID: https://orcid.org/0000-0002-2912-8695)
- Jordan Komisarow (ORCID: https://orcid.org/0000-0003-3919-7931)
- Margaret Johnson (ORCID: https://orcid.org/0000-0003-1208-622X)
- Gregory Chamberlin (ORCID: https://orcid.org/0000-0003-4306-3549)
- Anoop P. Patel (ORCID: https://orcid.org/0000-0001-7078-9535)
- David W. Jang (ORCID: https://orcid.org/0000-0003-4200-7174)
- Steven Cook
- Ralph Abi Hachem (ORCID: https://orcid.org/0009-0000-4007-8505)
- Benjamin D. Wissel (ORCID: https://orcid.org/0000-0002-8967-9296)
- Edwin Owolo (ORCID: https://orcid.org/0000-0001-9666-161X)
- Tanner J. Zachem (ORCID: https://orcid.org/0000-0002-3129-1133)
- Patrick J. Codd (ORCID: https://orcid.org/0000-0003-2939-849X)
- Courtney Rory Goodwin (ORCID: https://orcid.org/0000-0002-6540-2751)
- Annee Nguyen (ORCID: https://orcid.org/0000-0002-5550-9053)
- Derek G. Southwell (ORCID: https://orcid.org/0000-0001-6465-3869)
- Allan H. Friedman
- James E. Herndon
- Kerri‐Anne Crowell
Institutions
- Division of Materials Science and Engineering (AU)
- Duke University Hospital (US)
Publication Details
- Journal
- Journal of neurosurgery
- Published
- 2025-04-05
- DOI
- https://doi.org/10.3171/2024.12.jns242041
- Primary Topic
- Intracranial Aneurysms: Treatment and Complications
- Type
- article
- Field-Weighted Citation Impact
- 0.00