Role of Splenic and Hepatic Stiffness Measurements in Determining the Degree of Thrombocytopenia in Patients with chronic Liver cirrhosis

Background: The etiology of liver cirrhosis (LC) varies widely with many causes and fibrosis is the precursor of cirrhosis. Thrombocytopenia is common in advanced liver disease, as well as Splenomegaly. The degree of liver and spleen stiffness can be assessed noninvasively by liver stiffness measurements (LSM) called transient elastography (TE). Aim: to evaluate the relationship between spleen, liver stiffness measured by TE and the degree of thrombocytopenia in patients with LC. Methods: a cross-sectional study carried out on 50 patients suffering from compensated liver cirrhosis and has thrombocytopenia. Thrombocytopenia was categorized as mild (platelets count 75,000-150,000/µL), moderate (50,000-75,000/ µL) and severe (

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Publication Details

Journal
Benha Medical Journal
Published
2025-04-01
DOI
https://doi.org/10.21608/bmfj.2022.135478.1588
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
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article

Role of Splenic and Hepatic Stiffness Measurements in Determining the Degree of Thrombocytopenia in Patients with chronic Liver cirrhosis

Eman Abdelsameea, Sherif Negm, Medhat Khalif, Ghada Gamal
Benha Medical Journal
Liver Disease Diagnosis and Treatment
article

Role of Splenic and Hepatic Stiffness Measurements in Determining the Degree of Thrombocytopenia in Patients with chronic Liver cirrhosis

Eman Abdelsameea, Sherif Negm, Medhat Khalif, Ghada Gamal
article en

Abstract

Background: The etiology of liver cirrhosis (LC) varies widely with many causes and fibrosis is the precursor of cirrhosis. Thrombocytopenia is common in advanced liver disease, as well as Splenomegaly. The degree of liver and spleen stiffness can be assessed noninvasively by liver stiffness measurements (LSM) called transient elastography (TE). Aim: to evaluate the relationship between spleen, liver stiffness measured by TE and the degree of thrombocytopenia in patients with LC. Methods: a cross-sectional study carried out on 50 patients suffering from compensated liver cirrhosis and has thrombocytopenia. Thrombocytopenia was categorized as mild (platelets count 75,000-150,000/µL), moderate (50,000-75,000/ µL) and severe (

Benha Medical JournalVol. 42(4)
Benha University (EG), Liver Institute Northwest (US)
Good health and well-being
Openalex Percentile: Top 90%
Liver Disease Diagnosis and Treatment
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