Treatment with Ceftazidime-Avibactam for Lower Respiratory Tract Infections Caused by the Multidrug-Resistant Gram-Negative Bacteria in the Intensive Care Unit
CAZ-AVI can be used to treat LRTIs caused by MDR-GNB in the ICU. Higher APACHE II scores and coinfection with Aspergillus were associated with 28-day mortality, whereas a longer course of therapy was a protective factor. The nomogram can help clinicians predict CAZ-AVI outcomes.
Authors
- Zhi Geng (ORCID: https://orcid.org/0000-0003-1798-4475)
- Haobo Kong
- Min Liang (ORCID: https://orcid.org/0000-0002-0613-2077)
- Shufeng Yu (ORCID: https://orcid.org/0000-0002-2444-2642)
- Jingjing Pan (ORCID: https://orcid.org/0000-0003-2887-9881)
- Xiang Fang (ORCID: https://orcid.org/0009-0006-3958-990X)
Institutions
- Anhui Medical University (CN)
- Anhui Provincial Hospital (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Infection and Drug Resistance
- Published
- 2025-04-01
- DOI
- https://doi.org/10.2147/idr.s513168
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00