Icariside II induces ferroptosis through the down-regulation of SLC7A11 in ovarian cancer
Icariside II induces ferroptosis in OV by downregulating SLC7A11 expression in vitro and in vivo. Our study identified Icariside II as a promising therapeutic agent for the treatment of OV.
Authors
- Donglan Yuan
- Xiaotong Zhu (ORCID: https://orcid.org/0000-0002-9064-586X)
- Dengyun Nie (ORCID: https://orcid.org/0000-0001-6622-7513)
- Hong Yu (ORCID: https://orcid.org/0000-0001-6108-8921)
- Ting Guo (ORCID: https://orcid.org/0000-0002-3794-9346)
- Weiwei Song (ORCID: https://orcid.org/0000-0002-0243-0050)
Institutions
- Nanjing University (CN)
Publication Details
- Journal
- Journal of Ovarian Research
- Published
- 2025-04-05
- DOI
- https://doi.org/10.1186/s13048-025-01650-1
- Citations
- 2
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 1.87
Funders
- Nanjing Medical University