Metabolic profiling and early prediction models for gestational diabetes mellitus in PCOS and non-PCOS pregnant women

Untargeted metabolomics analysis revealed distinct metabolic patterns between PCOS patients and non-PCOS patients, particularly in pathways related to GDM. Based on these findings, we successfully constructed GDM prediction models for both PCOS and non-PCOS groups, offering a promising tool for clinical management and early intervention in high-risk populations.

Authors

Fei Hou (ORCID: https://orcid.org/0000-0001-8226-6635)
Can Cui (ORCID: https://orcid.org/0000-0001-9062-1588)
Zhiyan Wu (ORCID: https://orcid.org/0000-0001-7916-032X)
Hua Jin
Jinfeng Wang (ORCID: https://orcid.org/0000-0002-6687-9420)
Yingying Peng (ORCID: https://orcid.org/0000-0003-4611-0873)

Institutions

Jinan Maternity And Care Hospital (CN)
Qingzhou City People's Hospital (CN)
Weifang People's Hospital (CN)
Shandong Maternal and Child Health Hospital (CN)
Shandong First Medical University (CN)

Publication Details

Journal: European journal of medical research
Published: 2025-04-05
DOI: https://doi.org/10.1186/s40001-025-02526-2
Citations: 2
Primary Topic: Gestational Diabetes Research and Management
Type: article
Field-Weighted Citation Impact: 4.11

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article

Metabolic profiling and early prediction models for gestational diabetes mellitus in PCOS and non-PCOS pregnant women

Fei Hou, Can Cui, Zhiyan Wu, Hua Jin et al.

Apr 5, 2025

2 citations

European journal of medical research

Gestational Diabetes Research and Management

4.11

article

Metabolic profiling and early prediction models for gestational diabetes mellitus in PCOS and non-PCOS pregnant women

Fei Hou, Can Cui, Zhiyan Wu, Hua Jin, Jinfeng Wang, Yingying Peng

April 5, 2025article en

2 citations

Abstract

Untargeted metabolomics analysis revealed distinct metabolic patterns between PCOS patients and non-PCOS patients, particularly in pathways related to GDM. Based on these findings, we successfully constructed GDM prediction models for both PCOS and non-PCOS groups, offering a promising tool for clinical management and early intervention in high-risk populations.

European journal of medical researchVol. 30(1)

Jinan Maternity And Care Hospital (CN), Qingzhou City People's Hospital (CN), Weifang People's Hospital (CN), Shandong Maternal and Child Health Hospital (CN), Shandong First Medical University (CN)

Openalex Percentile: Top 8%

Gestational Diabetes Research and Management

4.11

DOI Open Access PDF OpenAlex

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Metabolic profiling and early prediction models for gestational diabetes mellitus in PCOS and non-PCOS pregnant women — Fei Hou, Can Cui, et al. · European journal of medical research (2025) | TGRS Research Map | TGRS