Impact of polymerization reaction conditions on the stability of naproxen sodium

Our findings indicate that NAP cannot be combined with the polymer during the polymerization process in extreme conditions of synthesis, specifically at temperatures of 70°C and in the presence of radicals, without undergoing decomposition. Nevertheless, further trials and tests are necessary to substantiate this hypothesis. One potential avenue for further investigation would be trials with alternative radical initiators, such as potassium persulfate (KPS).

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Publication Details

Journal
Polymers in Medicine
Published
2025-04-04
DOI
https://doi.org/10.17219/pim/202644
Primary Topic
Synthesis and properties of polymers
Type
article
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article

Impact of polymerization reaction conditions on the stability of naproxen sodium

Adrianna Złocińska, Agnieszka Gola
Polymers in Medicine
Synthesis and properties of polymers
article

Impact of polymerization reaction conditions on the stability of naproxen sodium

Adrianna Złocińska, Agnieszka Gola
article en

Abstract

Our findings indicate that NAP cannot be combined with the polymer during the polymerization process in extreme conditions of synthesis, specifically at temperatures of 70°C and in the presence of radicals, without undergoing decomposition. Nevertheless, further trials and tests are necessary to substantiate this hypothesis. One potential avenue for further investigation would be trials with alternative radical initiators, such as potassium persulfate (KPS).

Polymers in MedicineVol. 55(1)
Wroclaw Medical University (PL)
Openalex Percentile: Top 95%
Synthesis and properties of polymers
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