Serotonin promotes calcium accumulation and inhibits lipid accumulation in cultured goat mammary epithelial cells through HTR2A
5-HT inhibits lipid synthesis in GMECs while promoting an increase in cellular calcium levels, and this effect is mediated by the HTR2A receptor. Furthermorey, antagonists targeting HTR2A can reverse the inhibition of lipid synthesis and accumulation in cells.
Authors
- B. Li
- Kang Hu (ORCID: https://orcid.org/0000-0001-7217-0445)
- Yue Wang (ORCID: https://orcid.org/0000-0003-3021-7019)
- Zhifei Zhang (ORCID: https://orcid.org/0000-0002-1251-6667)
- Huiling Zheng
- Tumaresi Abuduwufuer
Institutions
- Northwest University (CN)
- Guangdong Academy of Agricultural Sciences (CN)
- Northwest Institute of Mechanical and Electrical Engineering (CN)
- Northwest A&F University (CN)
Publication Details
- Journal
- Animal Bioscience
- Published
- 2025-04-04
- DOI
- https://doi.org/10.5713/ab.24.0792
- Primary Topic
- Meat and Animal Product Quality
- Type
- article
- Field-Weighted Citation Impact
- 0.00