Molecular Mechanisms in Idiopathic Mitral Valve Chordae Tendineae Rupture: Insights from Transcriptome Analysis and Inflammation Evaluation
iRCT involves ECM remodeling, inflammation, and immune dysregulation, with identified hub genes offering potential therapeutic targets.
Authors
- Junfei Zhao (ORCID: https://orcid.org/0000-0002-4569-9797)
- Zhaolong Zhang (ORCID: https://orcid.org/0000-0003-3145-9730)
- Lishan Zhong (ORCID: https://orcid.org/0000-0001-8224-1614)
- Huanlei Huang (ORCID: https://orcid.org/0000-0003-0313-7785)
- Qiuji Wang
- Linbin Hua (ORCID: https://orcid.org/0009-0003-8581-7123)
- Yuxin Li (ORCID: https://orcid.org/0000-0001-9739-9860)
- Shanwen Pang (ORCID: https://orcid.org/0009-0007-4292-864X)
Institutions
- Key Laboratory of Guangdong Province (CN)
- Guangdong Academy of Medical Sciences (CN)
- Guangdong Provincial People's Hospital (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-04-01
- DOI
- https://doi.org/10.2147/jir.s510525
- Citations
- 1
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China