Clostridioides difficile concentration-dependant alterations in gut microbiota of asymptomatic infants
Asymptomatic carriage of C. difficile in neonates is not associated with significant gut microbiota alterations unless pathogen concentration is considered. Our findings suggest that elevated C. difficile proliferation occurs in dysbiotic infant gut microbiota, characterized by reduced alpha diversity and an increase in Escherichia.
Authors
- Jana Lozar Krivec (ORCID: https://orcid.org/0000-0002-6777-5607)
- Maja Rupnik (ORCID: https://orcid.org/0000-0003-1930-3290)
- Bojana Bogovič Matijašić (ORCID: https://orcid.org/0000-0003-0666-6981)
- Petra Bratina
- Tanja Obermajer (ORCID: https://orcid.org/0000-0003-4956-1928)
- Evgen Benedik (ORCID: https://orcid.org/0000-0002-6954-1118)
- Darja Paro‐Panjan (ORCID: https://orcid.org/0000-0001-7718-3392)
- Aleksander Mahnič (ORCID: https://orcid.org/0000-0002-6800-8549)
- Andreja Valcl
Institutions
- University of Ljubljana (SI)
- Ljubljana University Medical Centre (SI)
- University of Maribor (SI)
- Biotechnical Educational Centre Ljubljana (SI)
- National Laboratory of Health, Environment and Food (SI)
- Šolski center Slovenj Gradec (SI)
- Animal Hospital Postojna (SI)
Publication Details
- Journal
- Gut Pathogens
- Published
- 2025-04-04
- DOI
- https://doi.org/10.1186/s13099-025-00687-3
- Primary Topic
- Clostridium difficile and Clostridium perfringens research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Javna Agencija za Raziskovalno Dejavnost RS