Exploring CD4 +CD8 + double-positive T cells in canine allergy and health: A pilot study
DP T cells showed greater proliferation in food-allergic dogs compared to those with other allergic conditions like NFICAD. Despite these differences, overlapping results indicate that DP T cells are not a reliable screening test for distinguishing allergic from healthy dogs. While the test holds potential for identifying allergic phenotypes, it lacks sufficient diagnostic value for pinpointing specific allergens. Future studies with larger sample sizes and refined methods are needed to improve diagnostic accuracy.
Authors
- Eric Cox (ORCID: https://orcid.org/0000-0003-4281-2990)
- Bert Devriendt (ORCID: https://orcid.org/0000-0002-3222-8769)
- Elisa Maina
Institutions
- University of Bern (CH)
- Swedish University of Agricultural Sciences (SE)
- Ghent University (BE)
Publication Details
- Journal
- Veterinary Immunology and Immunopathology
- Published
- 2025-04-04
- DOI
- https://doi.org/10.1016/j.vetimm.2025.110924
- Primary Topic
- T-cell and B-cell Immunology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Bijzonder Onderzoeksfonds UGent