Formulation of Microencapsulated Neem Oil and Castor Oil in an Anti-Aging Cream

Introduction: Herbal oils and its formulas are in increasing demand in the cosmetic and pharmaceutical industry. The research paper highlights the potent anti-inflammatory, antioxidant, and antimicrobial capabilities of neem and castor oils. Objective: The objective of research work is to prepare oil-filled Microcapsules incorporated in a cream formulation. This formulation further subjected to analytical evaluation by sophisticated instrument. Methods: Microcapsule were prepared by ionic gelation process. The microcapsule containing cream was created using batches of varying concentrations, denoted as F1, F2, F3, F4 and F5. Further microcapsules morphology was studied by TGA, SEM, LE was calculated and FTIR was used to characterize manufactured microcapsules. As a part of biological study formulation was subjected for animal study and in vitro DPPH free radical scavenging assay. Results: A variety of parameters, including pH, spreadability, homogeneity, and viscosity, were used to evaluate each composition. Formulations F4 and F5, according to the study, had good spreadability, homogeneity with a decent look, good consistency, a pH of 7, no phase separation, and were easy to get rid of. Further these batches namely F4 and F5 was tested for non-irritancy using animal study according to CPCSEA guidelines. These investigations imply that the cream of the F5 batch has a safer and more stable composition, that might result in a synergistic effect. Conclusion: The F5 batch was showing best formulation in order to prevent aging of the skin, it can be served as a barrier for shielding the skin