Sanggenol L Activates Caspase and Inhibits the NF-κ B/JNK/ERK Signaling Pathway to Promote Apoptotic Cell Death in Colorectal Cancer Cells
The study results indicate that sanggenol L triggers caspase-induced apoptosis in colorectal cancer cells. Lastly, it was proposed that sanggenol L could help prevent colon cancer.
Authors
- Ran Luo (ORCID: https://orcid.org/0009-0006-0960-7118)
- Annamalai Vijayalakshmi
- Zhiyi Tang (ORCID: https://orcid.org/0000-0001-7463-694X)
- Jie Shu (ORCID: https://orcid.org/0000-0002-4922-8677)
- Ye Li (ORCID: https://orcid.org/0000-0001-7727-0875)
Institutions
- Annamalai University (IN)
- Kunming Medical University (CN)
- Kunming Children's Hospital (CN)
- The First Hospital of Kunming (CN)
Publication Details
- Journal
- Combinatorial Chemistry & High Throughput Screening
- Published
- 2025-04-04
- DOI
- https://doi.org/10.2174/0113862073369624250131053853
- Citations
- 1
- Primary Topic
- Bioactive natural compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.81