Emergence of Salmonella enterica carrying blaOXA-181 carbapenemase gene, Italy, 2021 to 2024
Between 2021 and 2024, we detected carbapenemase gene <i>blaOXA-181</i> in 16 of 11,398 <i>Salmonella enterica</i> (SE) isolates: 10 SE 1,4,[5],12:i:-, three Bovismorbificans, two London and one Rissen from pigs, humans, pork meat and wild roe deer. The gene was first detected in pig isolates, later in humans, suggesting zoonotic transmission. Phylogenetic analysis indicated that horizontal transfer, mainly through plasmids, contributed to the spread. These findings highlight a possible emerging public health threat and the importance of One Health surveillance.
Authors
- Martina Tambassi (ORCID: https://orcid.org/0000-0001-6775-2360)
- Elena Lavinia Diaconu (ORCID: https://orcid.org/0000-0002-2115-4311)
- Melissa Berni (ORCID: https://orcid.org/0000-0002-2396-465X)
- Laura Manni
- Patricia Alba (ORCID: https://orcid.org/0000-0002-9621-0955)
- R. Taddei
- Alessandra Dodi (ORCID: https://orcid.org/0000-0002-4029-2170)
- Laura Mazzera (ORCID: https://orcid.org/0000-0002-7106-6424)
- Simone Ambretti (ORCID: https://orcid.org/0000-0002-8358-339X)
- Antonio Battisti (ORCID: https://orcid.org/0000-0003-1308-199X)
- Virginia Carfora (ORCID: https://orcid.org/0000-0002-3835-4723)
- Massimiliano Vinci
- Luca Bolzoni (ORCID: https://orcid.org/0000-0001-8523-4460)
- Chiara Bracchi (ORCID: https://orcid.org/0000-0002-3966-6550)
- Erika Scaltriti (ORCID: https://orcid.org/0000-0003-2499-5930)
- Irene Venturelli (ORCID: https://orcid.org/0009-0005-5026-6274)
- Marina Morganti (ORCID: https://orcid.org/0000-0002-1521-2255)
- Stefano Pongolini (ORCID: https://orcid.org/0000-0002-4823-3562)
- Ilaria Menozzi (ORCID: https://orcid.org/0000-0001-9726-6769)
- Sara Angelone
Institutions
- University of Pavia (IT)
- Azienda Ospedaliero-Universitaria di Modena (IT)
- Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna "Bruno Ubertini" (IT)
- Azienda USL di Bologna (IT)
- Istituto Zooprofilattico Sperimentale delle Regioni Lazio e Toscana (IT)
- University of Bologna (IT)
Publication Details
- Journal
- Eurosurveillance
- Published
- 2025-04-03
- DOI
- https://doi.org/10.2807/1560-7917.es.2025.30.13.2500175
- Citations
- 3
- Primary Topic
- Salmonella and Campylobacter epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 3.49