Behavioral effects of three synthetic tryptamine derivatives in rodents
The locomotor depressant effects of the three synthetic tryptamine derivatives were similar to DOM, but not as potent. In the drug discrimination assay, only 4-OH-MIPT was substituted fully for DOM. These results support the possibility that 4-OH-MIPT has abuse liability similar to DOM, whereas 5-MeO-DBT and 5-Cl-DMT may not.
Authors
- Ritu A. Shetty
- Michael B. Gatch (ORCID: https://orcid.org/0000-0003-3474-211X)
- Nathalie Sumien (ORCID: https://orcid.org/0000-0002-0077-9873)
- Jeanne Priddy
- Michael J. Forster (ORCID: https://orcid.org/0000-0002-3284-2558)
- Rebecca Hill
Institutions
- University of North Texas (US)
- University of North Texas Health Science Center (US)
Publication Details
- Journal
- Journal of Psychopharmacology
- Published
- 2025-04-04
- DOI
- https://doi.org/10.1177/02698811251330737
- Primary Topic
- Psychedelics and Drug Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute on Drug Abuse