Identification of tryptophan metabolism-related biomarkers for nonalcoholic fatty liver disease through network analysis
CCL20, CD160 and CYP7A1 are tryptophan metabolism-related biomarkers of NAFLD, related to glycerol ester and cholesterol metabolism. We screened four compounds which co-target CCL29 and CYP7A1 to provide potential experimental drugs for NAFLD.
Authors
- Deju Zhang (ORCID: https://orcid.org/0000-0001-5671-3227)
- Guilin Ye
- Yanqing Ye (ORCID: https://orcid.org/0000-0003-4244-5385)
- Liefeng Wang (ORCID: https://orcid.org/0000-0003-4787-4533)
- Cuihua Jiang (ORCID: https://orcid.org/0000-0001-9207-9737)
- Xiaozhi Zhang (ORCID: https://orcid.org/0000-0002-3988-2181)
- Kaibo Hu (ORCID: https://orcid.org/0000-0002-0060-6729)
- Jing Zhang (ORCID: https://orcid.org/0000-0002-9449-6646)
- Bin Zhong (ORCID: https://orcid.org/0000-0002-2628-772X)
- Jianqi Liang
- Bin Zeng
- Peng Yu (ORCID: https://orcid.org/0009-0008-0345-5787)
- Jiajia Yang (ORCID: https://orcid.org/0000-0003-3869-4653)
Institutions
- Nanchang University (CN)
- Chinese University of Hong Kong (HK)
- Ganzhou People's Hospital (CN)
- Second Affiliated Hospital of Nanchang University (CN)
- Gannan Medical University (CN)
- First Affiliated Hospital of Gannan Medical University (CN)
- University of Hong Kong (HK)
- China Medical University (CN)
Publication Details
- Journal
- Endocrine Connections
- Published
- 2025-04-04
- DOI
- https://doi.org/10.1530/ec-24-0470
- Citations
- 1
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Jiangxi Province
- Education Department of Jiangxi Province
- Recruitment Program of Global Experts