Assessment of ventilation heterogeneity and particle deposition in asthmatics using combined SPECT/CT imaging and computational modeling approaches

Our cluster-informed CFPD-based approach enhances the understanding of ventilation heterogeneity in asthma and holds potential for refining strategies for inhalational therapies.

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Publication Details

Journal
European Journal of Pharmaceutical Sciences
Published
2025-04-04
DOI
https://doi.org/10.1016/j.ejps.2025.107093
Citations
3
Primary Topic
Inhalation and Respiratory Drug Delivery
Type
article
Field-Weighted Citation Impact
4.56
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article

Assessment of ventilation heterogeneity and particle deposition in asthmatics using combined SPECT/CT imaging and computational modeling approaches

Andrew Babiskin, Nizar N. Jarjour, Mario Castro, Eric A. Hoffman et al.
3 citations
European Journal of Pharmaceutical Sciences
Inhalation and Respiratory Drug Delivery
4.56
article

Assessment of ventilation heterogeneity and particle deposition in asthmatics using combined SPECT/CT imaging and computational modeling approaches

Andrew Babiskin, Nizar N. Jarjour, Mario Castro, Eric A. Hoffman, David W. Kaczka, Sean B. Fain, John V. Fahy, Jiwoong Choi, Mark L. Schiebler, SERPIL CEM ERZURUM, Minori Kinjo, Frank Li, Benjamin M. Smith, Bruce David Levy, Sally E. Wenzel, Ross Walenga, Alejandro P. Comellas, Sanghun Choi, Prathish K. Rajaraman, Ching-Long Lin, Elliot Israel, Xuan Zhang
article en
3 citations

Abstract

Our cluster-informed CFPD-based approach enhances the understanding of ventilation heterogeneity in asthma and holds potential for refining strategies for inhalational therapies.

European Journal of Pharmaceutical SciencesVol. 209
University of Iowa (US), Brigham and Women's Hospital (US), Cleveland Clinic (US), United States Food and Drug Administration (US), Center for Drug Evaluation and Research (US), University of Wisconsin–Madison (US), Harvard University (US), University of Kansas (US), University of Pittsburgh (US), University of California, San Francisco (US), McGill University Health Centre (CA), Kyungpook National University (KR), Columbia University (US)
Openalex Percentile: Top 6%
Inhalation and Respiratory Drug Delivery
4.56
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