Plasma nontargeted metabolomics study of H1N1 and H3N2 influenza in children
Distinct metabolomic profiles were identified in pediatric H1N1 and H3N2 influenza cases compared to healthy controls. Specific glycerophospholipid metabolites were closely associated with inflammatory and liver function markers, highlighting their potential as biomarkers for disease monitoring and early diagnosis.
Authors
- Chenrui Liu (ORCID: https://orcid.org/0009-0003-3393-0394)
- Jiayi Du
- Yufeng Zhang (ORCID: https://orcid.org/0000-0002-5882-1675)
- Jiaxin Li (ORCID: https://orcid.org/0000-0001-9328-8936)
- Xinyu Wang (ORCID: https://orcid.org/0000-0002-5022-784X)
- Yuan Chen (ORCID: https://orcid.org/0009-0004-5351-191X)
- Tao Li (ORCID: https://orcid.org/0000-0001-5080-3352)
- Yaping Li (ORCID: https://orcid.org/0000-0002-0574-6966)
- Xiaoli Jia (ORCID: https://orcid.org/0009-0003-1121-3845)
- Yuxin Li (ORCID: https://orcid.org/0000-0003-0303-062X)
- Huiling Deng (ORCID: https://orcid.org/0009-0003-1850-2690)
- Xiaoyan Wang (ORCID: https://orcid.org/0009-0002-1735-7148)
Institutions
- Yale University (US)
- Second Affiliated Hospital of Xi'an Jiaotong University (CN)
- Xi’an Children’s Hospital (CN)
- Shaanxi University of Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-04-04
- DOI
- https://doi.org/10.3389/fcimb.2025.1537726
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China