Graft Outcomes With or Without Use of Cortical Bone Graft for Nasal Floor Reconstruction in Unilateral Cleft Lip and Palate

<i>Objective</i>Evaluate the use of cortical bone grafts (CBGs) for nasal floor reconstruction on alveolar bone graft (ABG) outcomes in unilateral cleft lip and palate (UCLP).<i>Design</i>Retrospective cohort study.<i>Setting</i>North-American cleft centers.<i>Subjects</i>Fifty-three children with nonsyndromic UCLP treated with secondary ABG.<i>Methods</i>Center 1 (<i>n</i> = 23) utilized CBG for nasal floor reconstruction, while Centers 2 (<i>n</i> = 10), 3 (<i>n</i> = 10), and 4 (<i>n</i> = 10) did not. Occlusal radiographs, taken 6 to 18 months after ABG, were assessed by 6 calibrated raters using the Standardized Way to Assess Grafts (SWAG) Scale. Weighted kappa statistics measured intra and interrater reliabilities. SWAG scores comparisons in the apical, middle, and coronal thirds of the alveolar cleft were conducted between the centers. The Kruskal-Wallis test was used to determine significant differences, with a <i>P</i>-value of <.05 considered statistically significant.<i>Results</i>Intrarater reliability was very good (κ = 0.858), and interrater reliabilities were good (κ = 0.717). Significant differences were initially found in overall SWAG scores across centers (<i>P</i> = .003), with Center 1 achieving the highest mean overall SWAG score (5.16 ± 0.99) compared to Centers 2, 3, and 4 (4.48 ± 1.37, 4.58 ± 1.44, and 3.72 ± 0.65, respectively). Center 4 exhibited statistically significant lower scores compared to Centers1, 2, and 3, and was excluded from secondary analyses. After exclusion, no significant differences remained among Centers1, 2, and 3 (<i>P</i> = .135) for overall SWAG scores or apical third SWAG scores (where CBG is inserted). No significant differences were observed in the middle (<i>P</i> = .055) or coronal (<i>P</i> = .131) thirds across centers.<i>Conclusions</i>CBG in secondary ABG procedures for CUCLP patients showed outcomes comparable to cancellous-only grafts, with a trend toward improved apical scores in CBG-treated patients.

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Journal
The Cleft Palate-Craniofacial Journal
Published
2025-04-04
DOI
https://doi.org/10.1177/10556656251322619
Primary Topic
Cleft Lip and Palate Research
Type
article
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article

Graft Outcomes With or Without Use of Cortical Bone Graft for Nasal Floor Reconstruction in Unilateral Cleft Lip and Palate

Ana Mercado, Jean-Charles Doucet, Amr Alsabbagh, John Daskalogiannakis et al.
The Cleft Palate-Craniofacial Journal
Cleft Lip and Palate Research
article

Graft Outcomes With or Without Use of Cortical Bone Graft for Nasal Floor Reconstruction in Unilateral Cleft Lip and Palate

Ana Mercado, Jean-Charles Doucet, Amr Alsabbagh, John Daskalogiannakis, Kathy Russell, Ross E. Long, Scott Martyna, Ronald R. Hathaway
article en

Abstract

<i>Objective</i>Evaluate the use of cortical bone grafts (CBGs) for nasal floor reconstruction on alveolar bone graft (ABG) outcomes in unilateral cleft lip and palate (UCLP).<i>Design</i>Retrospective cohort study.<i>Setting</i>North-American cleft centers.<i>Subjects</i>Fifty-three children with nonsyndromic UCLP treated with secondary ABG.<i>Methods</i>Center 1 (<i>n</i> = 23) utilized CBG for nasal floor reconstruction, while Centers 2 (<i>n</i> = 10), 3 (<i>n</i> = 10), and 4 (<i>n</i> = 10) did not. Occlusal radiographs, taken 6 to 18 months after ABG, were assessed by 6 calibrated raters using the Standardized Way to Assess Grafts (SWAG) Scale. Weighted kappa statistics measured intra and interrater reliabilities. SWAG scores comparisons in the apical, middle, and coronal thirds of the alveolar cleft were conducted between the centers. The Kruskal-Wallis test was used to determine significant differences, with a <i>P</i>-value of <.05 considered statistically significant.<i>Results</i>Intrarater reliability was very good (κ = 0.858), and interrater reliabilities were good (κ = 0.717). Significant differences were initially found in overall SWAG scores across centers (<i>P</i> = .003), with Center 1 achieving the highest mean overall SWAG score (5.16 ± 0.99) compared to Centers 2, 3, and 4 (4.48 ± 1.37, 4.58 ± 1.44, and 3.72 ± 0.65, respectively). Center 4 exhibited statistically significant lower scores compared to Centers1, 2, and 3, and was excluded from secondary analyses. After exclusion, no significant differences remained among Centers1, 2, and 3 (<i>P</i> = .135) for overall SWAG scores or apical third SWAG scores (where CBG is inserted). No significant differences were observed in the middle (<i>P</i> = .055) or coronal (<i>P</i> = .131) thirds across centers.<i>Conclusions</i>CBG in secondary ABG procedures for CUCLP patients showed outcomes comparable to cancellous-only grafts, with a trend toward improved apical scores in CBG-treated patients.

The Cleft Palate-Craniofacial Journal
Dalhousie University (CA), Clinic for Special Children (US), Nationwide Children's Hospital (US), University of Toronto (CA), University of Michigan (US), Izaak Walton Killam Health Centre (CA), Kelowna General Hospital (CA), The Ohio State University (US)
Reduced inequalities
Openalex Percentile: Top 92%
Cleft Lip and Palate Research
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