Prehospital Tranexamic Acid and First 24-Hour Blood Product Transfusion in Patients with Isolated Traumatic Brain Injury
In subjects with iTBI, prehospital TXA may be associated with lower odds of red cell transfusion compared with placebo. This effect was likely mediated by treatment group imbalances in the percentage of subjects with a penetrating mechanism of injury, as well as the need for emergent neurosurgical intervention.
Authors
- Susan Rowell (ORCID: https://orcid.org/0000-0003-3054-401X)
- David Deshpande (ORCID: https://orcid.org/0000-0002-1963-7381)
- Rachel K. Nordgren (ORCID: https://orcid.org/0000-0003-3664-1208)
- Martin A. Schreiber (ORCID: https://orcid.org/0000-0002-4430-6779)
- Zachary C Newman
- Pierce E Pramuka
- Andrew Benjamin
- W Ian McKinley
- Claire E Barbosa
Institutions
- Uniformed Services University of the Health Sciences (US)
- Chicago Department of Public Health (US)
- University of Chicago (US)
Publication Details
- Journal
- Journal of the American College of Surgeons
- Published
- 2025-04-04
- DOI
- https://doi.org/10.1097/xcs.0000000000001401
- Citations
- 1
- Primary Topic
- Blood transfusion and management
- Type
- article
- Field-Weighted Citation Impact
- 0.77