The ultrafine powder of atractylodis macrocephalae rhizoma improves immune function in naturally aging rats by regulating the PI3K/Akt/NF-κB signaling pathway
These findings suggest that BZU may enhance lymphocyte proliferation by inhibiting the PI3K/Akt/NF-κB signaling pathway, correcting immune cell imbalances, reducing inflammatory responses, and ultimately enhancing immune function and potentially delaying aging.
Authors
- Jie Su (ORCID: https://orcid.org/0000-0002-1361-1180)
- Su Gao (ORCID: https://orcid.org/0000-0002-8807-9248)
- Guiyuan Lv (ORCID: https://orcid.org/0000-0003-2732-4905)
- Yu Wang
- Chen Suhong
- Yiqing Zhou (ORCID: https://orcid.org/0000-0002-6391-3259)
- Niu Zhuangwei
Institutions
- Zhejiang Chinese Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-04-04
- DOI
- https://doi.org/10.3389/fphar.2025.1550357
- Citations
- 1
- Primary Topic
- Traditional Chinese Medicine Analysis
- Type
- article
- Field-Weighted Citation Impact
- 2.38
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Zhejiang Province