Expression Patterns of Immune Checkpoint Molecules and Their Clinical Values in Gastric Neuroendocrine Neoplasms
We detected variable expression of the PD-L1, PD-L2, B7-H3, B7-H4, LGALS9, and CD155 proteins in g-NENs. These results suggest that the expression level of CD155 may be a vital indicator of OS in patients with g-NENs. B7 family ligands/receptors could be potential immunotherapeutic targets for g-NENs.
Authors
- Xingzhou Wang
- Daming Cai
- Shichao Ai (ORCID: https://orcid.org/0000-0002-9691-0281)
- Xiaofei Shen (ORCID: https://orcid.org/0000-0002-5816-1814)
- Shuang Fu (ORCID: https://orcid.org/0000-0002-5160-191X)
- Peng Song (ORCID: https://orcid.org/0000-0001-5165-0263)
- Mengjie Liang
- Meng Wang (ORCID: https://orcid.org/0000-0002-4970-8590)
- Heng Yu
- Xiaofeng Lu (ORCID: https://orcid.org/0009-0006-6164-8574)
- Wenxian Guan (ORCID: https://orcid.org/0000-0002-0207-1705)
- Feng Sun
- Jun Lü
Institutions
- Nanjing Drum Tower Hospital (CN)
Publication Details
- Journal
- Clinical and Translational Gastroenterology
- Published
- 2025-04-04
- DOI
- https://doi.org/10.14309/ctg.0000000000000842
- Citations
- 3
- Primary Topic
- Neuroendocrine Tumor Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 4.06