Influence of the Anti-Hyperlipidemia Effect of Fish Oil Supplement in High-Cholesterol Diet Rats

Complex fish oil capsule have been widely reported as a useful supplement to reduce fasting blood triglyceride levels in individuals with hyperlipidemia in high cholesterol diet (HCD) mice. The mice difference five groups (control, HCD, complex fish oil capsule dose 1X-flod, 2X-flod and 5X-flod) for six weeks. The evaluate complex fish oil use blood biochemical values, liver and feces assay. Thus feed a high-cholesterol diet resulted in significant dyslipidemia and fatty liver formation in experimental animals. Supplementation with 1, 2, or 5X-flod the dose of FO for 6-weeks resulted in a significant reduced in serum TG, TC, LDL-C and LDL-C/high-density lipoprotein cholesterol (HDL-C) ratio (p<0.05) and a significant decrease in TG and TC in the liver (p<0.05). By the experimental data can help reduce serum TG, TC and LDL-C concentrations, leading to a healthy effect on cardiovascular disease prevention.