Does Levosimendan hasten veno-arterial ECMO weaning? A propensity score matching analysis
In patients with non-postoperative cardiogenic shock supported by peripheral VA-ECMO, levosimendan was not associated with increased rates of successful VA-ECMO weaning or improved 30-day and 6-month bridge-free survival. Results from double-blinded randomized controlled trials are urgently needed to clarify the effectiveness and optimal timing of levosimendan in this specific population.
Authors
- David Levy (ORCID: https://orcid.org/0000-0001-9285-9610)
- Guillaume Hékimian (ORCID: https://orcid.org/0000-0003-3426-5720)
- Guillaume Lebreton (ORCID: https://orcid.org/0000-0003-4308-506X)
- Quentin Moyon (ORCID: https://orcid.org/0000-0002-0223-5191)
- Ouriel Saura (ORCID: https://orcid.org/0000-0002-3565-3509)
- Juliette Chommeloux
- Bruno Lévy (ORCID: https://orcid.org/0000-0002-7630-2908)
- Antoine Kimmoun (ORCID: https://orcid.org/0000-0002-5443-2074)
- David Hajage (ORCID: https://orcid.org/0000-0002-8475-4090)
- Pierre Hubert
- Nicolas Paulo (ORCID: https://orcid.org/0000-0001-6590-8384)
- Matthieu Schmidt (ORCID: https://orcid.org/0000-0002-2931-4412)
- Marc Pineton de Chambrun (ORCID: https://orcid.org/0000-0002-6321-858X)
- Melchior Gautier
- Alain Combes
- Charles Edouard Luyt
- Grégoire Del Marmol
Institutions
- Université Sorbonne Nouvelle (FR)
- Sorbonne Université (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Pitié-Salpêtrière Hospital (FR)
- Fondation pour l’innovation en Cadiométabolisme et Nutrition (FR)
- Réanimation et soins intensifs du patient en Insuffisance respiratoire aigüe
- Université de Lorraine (FR)
Publication Details
- Journal
- Annals of Intensive Care
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1186/s13613-025-01457-9
- Citations
- 6
- Primary Topic
- Mechanical Circulatory Support Devices
- Type
- article
- Field-Weighted Citation Impact
- 4.04