Development and validation of basement membrane-related signatures for predicting postoperative recurrence, tumor microenvironment and drug candidates in chordomas
This study explored the critical role of BM-related genes in skull base chordoma, which affected postoperative recurrence and maligant behavior of chordoma via the PI3K-Akt signaling pathway.
Authors
- Qian Liu (ORCID: https://orcid.org/0000-0002-8398-1021)
- Jiwei Bai (ORCID: https://orcid.org/0000-0003-0790-2069)
- Tianshun Ma (ORCID: https://orcid.org/0000-0002-9588-7585)
- Mingxuan Li (ORCID: https://orcid.org/0000-0002-8382-1124)
- Sida Zhao (ORCID: https://orcid.org/0000-0002-3145-705X)
- Yide Liu (ORCID: https://orcid.org/0000-0001-9268-3555)
- Xing Liu (ORCID: https://orcid.org/0000-0002-5786-2838)
- Tianhao Zhang (ORCID: https://orcid.org/0000-0003-3456-8262)
- Yazhuo Zhang (ORCID: https://orcid.org/0000-0002-8583-2580)
- Xijia Zhang
Institutions
- Capital Medical University (CN)
- Beijing Tian Tan Hospital (CN)
- Beijing Institute of Neurosurgery (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-04-03
- DOI
- https://doi.org/10.1186/s12885-025-14006-1
- Citations
- 1
- Primary Topic
- Bone Tumor Diagnosis and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.67
Funders
- National Natural Science Foundation of China