Risk factors for clazosentan-induced fluid retention in subarachnoid hemorrhage from the Japanese adverse event database
Clazosentan-induced fluid retention occurred more frequently in older adult patients. Clazosentan combined with fasudil hydrochloride increased the incidence of fluid retention. These findings can guide pharmacological treatment of cerebral vasospasm in patients with subarachnoid hemorrhage.
Authors
- Tomoaki Ishida (ORCID: https://orcid.org/0000-0002-1352-0123)
- Fuka Aizawa
- Rie Ando‐Matsuoka
- Tetsuya Ueba
- Takahiro Niimura (ORCID: https://orcid.org/0000-0003-2033-4246)
- Yu Kawanishi
- Mitsuhiro Goda (ORCID: https://orcid.org/0000-0001-5345-1479)
- Tomohito Kadota
- Shinji Abe (ORCID: https://orcid.org/0000-0003-0237-6047)
- Yuki Izawa‐Ishizawa (ORCID: https://orcid.org/0000-0002-8178-9028)
- Hitoshi Fukuda (ORCID: https://orcid.org/0000-0003-3803-8242)
- Keisuke Ishizawa
- Kei Kawada (ORCID: https://orcid.org/0000-0003-1397-6128)
- Kenta Yagi (ORCID: https://orcid.org/0000-0003-0869-5786)
- Toshihiko Yoshioka
Institutions
- Tokushima University Hospital (JP)
Publication Details
- Journal
- Journal of Stroke and Cerebrovascular Diseases
- Published
- 2025-04-04
- DOI
- https://doi.org/10.1016/j.jstrokecerebrovasdis.2025.108296
- Citations
- 3
- Primary Topic
- Intracranial Aneurysms: Treatment and Complications
- Type
- article
- Field-Weighted Citation Impact
- 4.17