Identification of AIF1 as a protein target of notoginsenosides in brain tissue of mice with intracerebral hemorrhage based on hapten immunoaffinity fishing technique
Our study proposed a new technology for screening natural small molecule protein targets, and successfully identified AIF1 as a protein target of notoginsenosides, providing a chemical and biological basis for further research into targeting AIF1 to treat ICH.
Authors
- Yunan Zhao (ORCID: https://orcid.org/0000-0003-4944-8765)
- Cuihua Chen (ORCID: https://orcid.org/0000-0001-7722-2160)
- Wei Qin (ORCID: https://orcid.org/0000-0003-2161-387X)
- Zhu Zhu (ORCID: https://orcid.org/0009-0008-2276-5000)
- Lin Chen (ORCID: https://orcid.org/0000-0001-7673-0438)
- Chu Li (ORCID: https://orcid.org/0009-0008-3392-3852)
- Feiyan Chen (ORCID: https://orcid.org/0000-0002-8264-5501)
- Qi Yao (ORCID: https://orcid.org/0000-0001-5275-0100)
- Qianlin Li
Institutions
- Nanjing University of Chinese Medicine (CN)
Publication Details
- Journal
- Journal of Ginseng Research
- Published
- 2025-04-04
- DOI
- https://doi.org/10.1016/j.jgr.2025.04.001
- Primary Topic
- Intracerebral and Subarachnoid Hemorrhage Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00