Catalyst-free synthesis of 1,2,3-triazole-N-oxide derivatives using <i>tert</i>-butyl nitrite: a novel strategy and synthetic applications
A simple, metal-free method has been developed to synthesize novel 1,2,3-triazole-N-oxide derivatives. In this reaction, <i>t</i>-BuONO serves as a NO source, with environmentally friendly solvents such as EtOH and H<sub>2</sub>O employed as additives. Control experiments provided valuable insights into the reaction mechanism. Furthermore, 1,2,3-triazole-N-oxides demonstrated versatility in synthetic transformations.
Authors
- Karuppaiah Perumal
- Bhaskaran Shankar (ORCID: https://orcid.org/0000-0001-8234-3645)
- Subburethinam Ramesh
- Markabandhu Shanthi
- Vijayakumar Hemamalini
Institutions
- SASTRA University (IN)
Publication Details
- Journal
- RSC Advances
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5ra01327e
- Citations
- 1
- Primary Topic
- Chemistry and Chemical Engineering
- Type
- article
- Field-Weighted Citation Impact
- 0.86
Funders
- Department of Science and Technology, Ministry of Science and Technology, India
- Science and Engineering Research Board