Association of free-water imaging data for the cholinergic nucleus with the motor function and subtypes in Parkinson’s disease
Tremor and rigidity subscores were correlated with Ch4 FW imaging data. Moreover, Ch4 FW imaging predicted the motor subtype at the 4-year follow-up, especially identifying potential postural instability and gait difficulty (PIGD) subtype converters from the TD group.
Authors
- Jun Tian (ORCID: https://orcid.org/0000-0003-4950-3963)
- Baorong Zhang (ORCID: https://orcid.org/0000-0002-8099-7407)
- Shanhu Xu (ORCID: https://orcid.org/0000-0003-3879-024X)
- Xiaoli Liu (ORCID: https://orcid.org/0000-0002-6204-4485)
- Xiaoli Si (ORCID: https://orcid.org/0000-0003-3562-2056)
- Miao Cai (ORCID: https://orcid.org/0000-0002-9439-3380)
- Fengli Fu
Institutions
- Zhejiang Hospital (CN)
- Second Affiliated Hospital of Zhejiang University (CN)
- First Affiliated Hospital Zhejiang University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-04-04
- DOI
- https://doi.org/10.3389/fneur.2025.1477827
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- National Health Commission of the People's Republic of China
- National Key Research and Development Program of China