Chronic motoneuronal activation enhanced axonal regeneration and functional recovery after brachial plexus injury
We have established a chronic chemogenetic method to activate hM3Dq<sup>+</sup> motor neurons after brachial plexus injury, which accelerates axonal regeneration and enhances functional recovery. This strategy holds promise as a clinical therapeutic approach for treating nervous system injuries.
Authors
- Jiang Shao (ORCID: https://orcid.org/0009-0008-0571-8683)
- Ke Zhong (ORCID: https://orcid.org/0000-0003-3664-9234)
- Jiajia Wu (ORCID: https://orcid.org/0000-0002-3970-596X)
- Zhen Wu (ORCID: https://orcid.org/0000-0002-7081-6430)
- Yu Huang (ORCID: https://orcid.org/0000-0003-3699-4708)
- Pingzhen Wu
- Lihua Zhou
- Wutian Wu
- Shiqin Lv
Institutions
- Sun Yat-sen University (CN)
- Jinan University (CN)
- Shenzhen University (CN)
- Sun Yat-sen Memorial Hospital (CN)
- Hongzhiwei Technology (China) (CN)
Publication Details
- Journal
- Journal of Orthopaedic Translation
- Published
- 2025-04-04
- DOI
- https://doi.org/10.1016/j.jot.2025.02.007
- Citations
- 1
- Primary Topic
- Nerve Injury and Rehabilitation
- Type
- article
- Field-Weighted Citation Impact
- 2.01