Exploring the impact of opioid use on outcomes in allogeneic hematopoietic stem cell transplantation
In our study, we found a correlation between intense opioid use in alloHCT patients and worse overall survival, particularly concerning higher relapse rates. These findings highlight the need for further research into pain management strategies to improve outcomes and reduce potential toxicity.
Authors
- Mats Remberger (ORCID: https://orcid.org/0000-0003-0520-4312)
- Abel Santos Carreira (ORCID: https://orcid.org/0000-0003-4400-0224)
- Igor Novitzky‐Basso (ORCID: https://orcid.org/0000-0003-3748-3117)
- Refik Saskin (ORCID: https://orcid.org/0000-0002-8641-7725)
- Tommy Alfaro Moya (ORCID: https://orcid.org/0000-0003-4171-4678)
- Jonas Mattsson (ORCID: https://orcid.org/0000-0002-2163-6644)
- Shiyi Chen (ORCID: https://orcid.org/0009-0002-6619-2909)
Institutions
- University Health Network (CA)
- Uppsala University Hospital (SE)
- Princess Margaret Cancer Centre (CA)
- Institut Català d'Oncologia (ES)
- Institute for Clinical Evaluative Sciences (CA)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-04-04
- DOI
- https://doi.org/10.1371/journal.pone.0321073
- Primary Topic
- Pain Management and Opioid Use
- Type
- article
- Field-Weighted Citation Impact
- 0.00