Features of the use of combined oral contraceptives for the correction of premenstrual syndrome

Annotation. Premenstrual syndrome (PMS) is a set of cognitive, physical, and affective symptoms that occur during the luteal phase of the menstrual cycle and disappear at the beginning of menstruation. Its more severe variant is premenstrual dysphoric disorder (PMDD). The aim of the work is to investigate the effects of combined oral contraceptives and their effectiveness and safety for the correction of PMS and PMDD. A retrospective analysis of the scientific literature was carried out using the following sources: PubMed, ReseachGate, Science Direct, Web of Science, Cochrane. The majority of publications published in the last five years (2019-2024) were selected for the study. Both syndromes are believed to be caused by cyclical changes in progesterone production. Combined oral contraceptives (COCs) are considered one of the treatment options for PMS and PMDD, as the drugs of this group contain synthetic estradiol and progestin, which have a complex effect on the hypothalamic-pituitary-ovarian system.