Experimental study on the effect of «Kаthomas» on the healing process of traumatic stomatitis in rats

Annotation. The study of traumatic stomatitis and other lesions of the oral mucosa is a relevant medical issue today that requires further research. Scientific findings in this field can contribute to the development of more effective methods for diagnosing, preventing, and treating traumatic injuries of the oral mucosa, thereby improving patients quality of life and reducing the risk of complications. The aim of our study was to investigate the healing characteristics of traumatic stomatitis when using kathomas. The research was conducted on 20 male albino rats of a standard breeding colony in the vivarium of Vinnytsia National Pirogov Memorial Medical University. The rats were divided into two groups: control group (10 healthy rats with traumatic stomatitis of the oral mucosa, induced by a standardized injury); comparison group (10 rats with traumatic stomatitis of the oral mucosa, treated with kathomas). The results showed that complete healing (100%) of standardized traumatic wounds of the cheek mucosa in the control group occurred on day 13, whereas in the comparison group, where kathomas was used, complete healing was observed on day 11. The reduction in healing time and the positive wound healing dynamics indicate that in animals receiving daily administration of kathomas, the epithelialization process was significantly faster compared to the control group, where spontaneous healing of oral mucosal wounds occurred without external influence. Kathomas should be the treatment of choice for improving the healing of traumatic stomatitis in a comprehensive treatment approach, as it accelerates epithelialization and reduces the number of complications associated with stomatitis.