Study of the indicators of physicochemical properties of oral fluid in patients with malabsorption syndrome

Annotation. The main role in the processes of interaction of organs and tissues in the biological environment of the oral cavity is played by the properties of oral fluid. At the same time, the issues of physicochemical properties of mixed saliva, which are important in the development of dental diseases associated with malabsorption syndrome, have not been studied sufficiently. The aim of the work is to study the physicochemical properties of oral fluid in patients with combined lesions of teeth, periodontal tissues and oral mucosa and malabsorption syndrome. 34 children and adolescents and 28 patients aged 25 to 64 years with malabsorption syndrome were examined. The control group consisted of: 34 healthy children and adolescents and 29 practically healthy individuals aged 25 to 64 years. The salivation rate was measured, the pH of the oral fluid was determined, the viscosity of mixed saliva and the buffer capacity were studied. The statistical processing of the results was carried out by methods of variational statistics using Student's reliability criteria. The study of the salivation rate index allowed us to establish a significant decrease in the level of its secretion relative to the control group from 37.5% to 45.4% in children and adolescents and 3.5 times in adult patients with malabsorption. The determination of the viscosity index revealed an identical statistically significant increase in the main group compared to the control group. When analyzing the results of the pH of the oral cavity, a significant decrease in the concentration of hydrogen ions in the mixed saliva of all patients of the main group was found, which ranged from 6.15±0.34 to 6.22±0.25 (p<0.05) relative to healthy individuals. The low capacity of the bicarbonate buffer of the examined patients of the main group compared to the control group indicated insufficient protection against the action of acids. Therefore, a significant decrease in the salivation rate with an increase in saliva viscosity against the background of an imbalance of acids and alkalis and a low ability to neutralize them in the oral cavity of patients with malabsorption syndrome creates conditions for the development of multiple dental caries, periodontal diseases and oral mucosa. The prospect of further research is to study the state of the oral microbiocenosis in these patients.