Development and validation of hierarchical signature for precision individualized therapy based on the landscape associated with necroptosis in clear cell renal cell carcinoma

The necroptosis-related signature we constructed can accurately predict the prognosis of ccRCC patients and further provide clues for targeted, individualized therapy.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2025-04-04
DOI
https://doi.org/10.3389/fphar.2025.1470145
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Development and validation of hierarchical signature for precision individualized therapy based on the landscape associated with necroptosis in clear cell renal cell carcinoma

Liangmin Fu, Lei Dai, Junshang Dai, Juan Lin et al.
Frontiers in Pharmacology
Ferroptosis and cancer prognosis
article

Development and validation of hierarchical signature for precision individualized therapy based on the landscape associated with necroptosis in clear cell renal cell carcinoma

Liangmin Fu, Lei Dai, Junshang Dai, Juan Lin, Zhiping Tan, Junhang Luo, Jinhuan Wei, Wei Chen, G YAO
article en

Abstract

The necroptosis-related signature we constructed can accurately predict the prognosis of ccRCC patients and further provide clues for targeted, individualized therapy.

Frontiers in PharmacologyVol. 16
Central South University (CN), Sun Yat-sen University (CN), Chinese University of Hong Kong (HK), The First Affiliated Hospital, Sun Yat-sen University (CN), Third Affiliated Hospital of Sun Yat-sen University (CN), Second Xiangya Hospital of Central South University (CN)
No poverty
Openalex Percentile: Top 90%
Ferroptosis and cancer prognosis
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