Clinical and pathological outcomes of deferred nephrectomy in patients with metastatic and locally advanced RCC after immune checkpoint inhibitors
Deferred CN following ICB therapy is feasible. Extensive necrosis in the resected surgical specimen after ICB-based therapy requires further investigation as a prognostic marker for durable responses off systemic therapy.
Authors
- Elizabeth Ryan (ORCID: https://orcid.org/0000-0001-9367-4204)
- Brian I. Rini (ORCID: https://orcid.org/0000-0002-2212-080X)
- Kelvin A. Moses (ORCID: https://orcid.org/0000-0003-3231-2941)
- Jennifer Gordetsky (ORCID: https://orcid.org/0000-0002-0745-2160)
- Daniel Joyce (ORCID: https://orcid.org/0000-0003-4365-8622)
- Daniel A. Barocas (ORCID: https://orcid.org/0000-0002-7775-9205)
- Kerry Schaffer (ORCID: https://orcid.org/0000-0002-0097-1574)
- Kathryn E. Beckermann (ORCID: https://orcid.org/0000-0002-4616-6140)
- Amy N. Luckenbaugh (ORCID: https://orcid.org/0000-0001-6598-9372)
- Sam S. Chang (ORCID: https://orcid.org/0000-0001-6195-5386)
- Morgan Lambrecht
- Paulo Siqueira Amaral (ORCID: https://orcid.org/0009-0003-3205-3799)
Institutions
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- The Oncologist
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1093/oncolo/oyaf004
- Citations
- 2
- Primary Topic
- Renal cell carcinoma treatment
- Type
- article
- Field-Weighted Citation Impact
- 3.04