Updated progression of honokiol in lung cancer treatment
In summary, Honokiol (HNK) is a biphenolic natural compound with significant anti-lung cancer properties. Its pharmacological characteristics, including the regulation of various molecular targets and the inhibition of key enzymes and kinases, make it a promising agent for the treatment of lung cancer. Emerging research supports its ability to prevent the progression of lung cancer, either alone or in combination with other therapies. Additionally, nanotechnologies have been used to modify HNK, potentially enhancing its efficacy in the treatment of lung cancer. This review highlights the various studies documenting the anti-lung cancer effects of HNK, underscoring its potential as a novel and effective therapy for this deadly disease.
Authors
- Wei Zhao (ORCID: https://orcid.org/0000-0003-2421-7311)
- Na Huang (ORCID: https://orcid.org/0000-0001-5799-1894)
- Ziwei Gao (ORCID: https://orcid.org/0000-0002-2547-9375)
- Yuping Yang (ORCID: https://orcid.org/0009-0002-6918-906X)
Institutions
- Chengdu Medical College (CN)
- First Affiliated Hospital of Chengdu Medical College (CN)
Publication Details
- Journal
- Journal of Pharmacy and Pharmacology
- Published
- 2025-04-04
- DOI
- https://doi.org/10.1093/jpp/rgaf007
- Citations
- 1
- Primary Topic
- Magnolia and Illicium research
- Type
- article
- Field-Weighted Citation Impact
- 1.03