Leveraging clinical indications and demographics to improve multilabel abnormality classification in 3D chest CT scans

The increasing number of Computed Tomography (CT) scan examinations coupled with the time-intensive nature of manual analysis highlights the need for efficient automated analysis methods to assist radiologists in detecting anomalies. While state-of-the-art deep learning approaches directly classifies abnormalities from three-dimensional (3D) CT images, radiologists also rely on clinical indications and patient demographics such as age and sex for diagnosis. We propose a multimodal model that integrates 3D chest CT scans, clinical information reports, patient age and sex to improve multi-label abnormality classification. Our approach leverages both imaging and non-imaging data by combining visual and textual neural networks. We extend our work by conducting an ablation study on a public dataset to evaluate and demonstrate the efficacy of our approach.

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Published
2025-04-04
DOI
https://doi.org/10.1117/12.3046901
Primary Topic
Radiomics and Machine Learning in Medical Imaging
Type
article
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article

Leveraging clinical indications and demographics to improve multilabel abnormality classification in 3D chest CT scans

Olivier Nempont, Carole Lazarus, Loïc Boussel, Theo Di Piazza
Radiomics and Machine Learning in Medical Imaging
article

Leveraging clinical indications and demographics to improve multilabel abnormality classification in 3D chest CT scans

Olivier Nempont, Carole Lazarus, Loïc Boussel, Theo Di Piazza
article en

Abstract

The increasing number of Computed Tomography (CT) scan examinations coupled with the time-intensive nature of manual analysis highlights the need for efficient automated analysis methods to assist radiologists in detecting anomalies. While state-of-the-art deep learning approaches directly classifies abnormalities from three-dimensional (3D) CT images, radiologists also rely on clinical indications and patient demographics such as age and sex for diagnosis. We propose a multimodal model that integrates 3D chest CT scans, clinical information reports, patient age and sex to improve multi-label abnormality classification. Our approach leverages both imaging and non-imaging data by combining visual and textual neural networks. We extend our work by conducting an ablation study on a public dataset to evaluate and demonstrate the efficacy of our approach.

Hospices Civils de Lyon (FR), Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé (FR), Philips (France) (FR)
Openalex Percentile: Top 90%
Radiomics and Machine Learning in Medical Imaging
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Leveraging clinical indications and demographics to improve multilabel abnormality classification in 3D chest CT scans — Olivier Nempont, Carole Lazarus, et al. · (2025) | TGRS Research Map | TGRS