Study on Ceftazidime-Avibactam with Aztreonam Combination Treatment in Carbapenem-Resistant <i>Klebsiella pneumoniae</i> in Tertiary Care Hospital in India
Background and Aim: Recently, the rise in various carbapenemases in Enterobacteriaceae poses a significant challenge to the healthcare systems and limits the treatment options.This study aimed to evaluate different assays such as disc diffusion, VITEK, and Rapidec Carba NP test for the carbapenemase detection, and investigate the synergistic effects of ceftazidimeavibactam (CAZ/AVI) and aztreonam (AZM) combination therapy using the E-strip method. Materials and Methods:This prospective study was conducted on the samples collected from January 2023 to February 2024 at the Department of Microbiology, Central Laboratory Sree Balaji, Medical College and Hospital
Authors
- R. Praveena (ORCID: https://orcid.org/0000-0002-2327-7518)
- Sharon Christina (ORCID: https://orcid.org/0009-0005-3213-6054)
Institutions
- Bharath University (IN)
Publication Details
- Journal
- Iranian Journal of Medical Microbiology
- Published
- 2024-09-09
- DOI
- https://doi.org/10.30699/ijmm.18.4.257
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00