A case of lingual lymphoma in a dog treated with oclacitinib

Lingual canine T-zone lymphoma (TZL) is a rare form of extranodal canine lymphoma. Seven-years and 5 months old, spayed female toy poodle presented with a red swollen mass on the tongue. A punch biopsy of the lesion was conducted, followed by histopathological and immunohistochemical analyses. Despite the absence of a lymph node excisional biopsy, the case was diagnosed as canine lingual TZL. Although there is no established treatment for lingual TZL, treatment often follows TZL protocols. In this case, the tongue lesion improved after the administration of oclacitinib, a drug approved for canine atopic dermatitis. We present this case due to its successful management with oclacitinib, without the use of conventional anticancer therapy.

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Publication Details

Journal
Journal of Veterinary Medical Science
Published
2025-01-01
DOI
https://doi.org/10.1292/jvms.24-0432
Citations
1
Primary Topic
Veterinary Oncology Research
Type
article
Field-Weighted Citation Impact
1.52

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article

A case of lingual lymphoma in a dog treated with oclacitinib

Takuya Mizuno, Masaya Igase, Kazumi Nibe, Shohei NISHIMORI et al.
1 citations
Journal of Veterinary Medical Science
Veterinary Oncology Research
1.52
article

A case of lingual lymphoma in a dog treated with oclacitinib

Takuya Mizuno, Masaya Igase, Kazumi Nibe, Shohei NISHIMORI, Kumiko OKANO
article en
1 citations

Abstract

Lingual canine T-zone lymphoma (TZL) is a rare form of extranodal canine lymphoma. Seven-years and 5 months old, spayed female toy poodle presented with a red swollen mass on the tongue. A punch biopsy of the lesion was conducted, followed by histopathological and immunohistochemical analyses. Despite the absence of a lymph node excisional biopsy, the case was diagnosed as canine lingual TZL. Although there is no established treatment for lingual TZL, treatment often follows TZL protocols. In this case, the tongue lesion improved after the administration of oclacitinib, a drug approved for canine atopic dermatitis. We present this case due to its successful management with oclacitinib, without the use of conventional anticancer therapy.

Journal of Veterinary Medical ScienceVol. 87(5)
Yamaguchi University (JP), Fujifilm (Japan) (JP), Hoshigaoka Medical Center (JP), Japan Small Animal Medical Center (JP), Kawasaki Medical School Hospital (JP)
University of Tokyo
Quality Education
Openalex Percentile: Top 20%
Veterinary Oncology Research
1.52
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A case of lingual lymphoma in a dog treated with oclacitinib — Takuya Mizuno, Masaya Igase, et al. · Journal of Veterinary Medical Science (2025) | TGRS Research Map | TGRS