Two Cases of Esophageal Mucosal Damage Observed after Peroral Endoscopic Myotomy for Esophageal Motility Disorders
This report presents two cases of esophageal mucosal damage following peroral endoscopic myotomy (POEM) for esophageal motility disorders. In the first case, delayed perforation and mediastinitis occurred on postoperative day 15 and the patient was treated with endoscopic clipping and antibiotics. In the second case, although no perforation was observed, extensive mucosal injury developed the day after POEM which was successfully managed by fasting and antibiotic therapy. These findings highlight the need for careful patient management to minimize the risks associated with POEM, while maximizing its therapeutic benefits.
Authors
- Hiroyuki Sakae (ORCID: https://orcid.org/0000-0002-7494-6347)
- Takuya Satomi (ORCID: https://orcid.org/0000-0003-0722-4739)
- Yoshiro Kawahara (ORCID: https://orcid.org/0000-0002-0509-251X)
- Masaya Iwamuro (ORCID: https://orcid.org/0000-0002-1757-5754)
- Shoichiro Hirata
- Kenta Hamada (ORCID: https://orcid.org/0000-0003-0768-3783)
- Motoyuki Otsuka (ORCID: https://orcid.org/0000-0003-2869-2881)
- Noriaki Manabe (ORCID: https://orcid.org/0000-0002-5010-3708)
- Seiji Kawano (ORCID: https://orcid.org/0000-0002-7807-5147)
- Tomohiro Kamio
Institutions
- Okayama University (JP)
- Kawasaki Medical School (JP)
Publication Details
- Journal
- Internal Medicine
- Published
- 2025-04-04
- DOI
- https://doi.org/10.2169/internalmedicine.4943-24
- Primary Topic
- Gastroesophageal reflux and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00