Knowledge, attitude and practice toward liraglutide and semaglutide among endocrinology medical staff

Semaglutide and liraglutide are commonly used to address metabolic disorders, but differ in usage, clinical efficacy and safety profiles. Endocrinology medical staff are crucial in ensuring the appropriate administration, but their knowledge, attitude, and practice (KAP) towards these medications have been underexplored. The study aimed to investigate their KAP toward liraglutide and semaglutide. A cross-sectional study was performed from September to December 2023 at the First People's Hospital of Jiujiang. Endocrinology medical staff completed a self-administered questionnaire for KAP assessment regarding liraglutide and semaglutide. A total of 265 participants were enrolled (mean age: 36.31 ± 8.17 years old), including 134 (50.57%) males. The average scores were as follows: knowledge 11.77 ± 3.37 (range: 0-16), attitude 39.30 ± 4.61 (range: 10-50), and practice 27.70 ± 5.52 (range: 7-35). The structural equation model (SEM) showed that knowledge significantly influenced attitude (β = 0.976, P < 0.001) and practice (β = 1.289, P < 0.001). Additionally, attitude had a significant effect on practice (β = 0.627, P < 0.001). This study revealed deficiencies in the KAP scores among endocrinology medical staff, emphasizing the necessity for targeted strategies to improve professional proficiency with liraglutide and semaglutide.