Discovery of <i>bis</i> -chalcones and <i>bis</i> -pyrimidines as potential urease inhibitors: from synthesis to computational insights

This study provides valuable insights into the development of target compounds as promising urease inhibitors. These findings suggest their potential therapeutic applications for urease-related disorders.

Authors

Amina Sadiq
Mohamed I. A. Othman (ORCID: https://orcid.org/0000-0002-0405-8918)
Nafeesa Naeem (ORCID: https://orcid.org/0000-0002-6647-9697)
Nehal Rana (ORCID: https://orcid.org/0000-0002-4595-0099)
Ehsan Ullah Mughal (ORCID: https://orcid.org/0000-0001-9463-9398)
Sumera Zaib

Institutions

University of Central Punjab (PK)
Government College Women University Sialkot
King Khalid University (SA)
University of Gujrat (PK)

Publication Details

Journal: Future Medicinal Chemistry
Published: 2025-04-04
DOI: https://doi.org/10.1080/17568919.2025.2485870
Primary Topic: Synthesis and biological activity
Type: article
Field-Weighted Citation Impact: 0.00

Funders

King Khalid University

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article

Discovery of bis -chalcones and bis -pyrimidines as potential urease inhibitors: from synthesis to computational insights

Amina Sadiq, Mohamed I. A. Othman, Nafeesa Naeem, Nehal Rana et al.

Apr 4, 2025

Future Medicinal Chemistry

Synthesis and biological activity

article

Discovery of bis -chalcones and bis -pyrimidines as potential urease inhibitors: from synthesis to computational insights

Amina Sadiq, Mohamed I. A. Othman, Nafeesa Naeem, Nehal Rana, Ehsan Ullah Mughal, Sumera Zaib

April 4, 2025article en

Abstract

This study provides valuable insights into the development of target compounds as promising urease inhibitors. These findings suggest their potential therapeutic applications for urease-related disorders.

Future Medicinal ChemistryVol. 17(8)

University of Central Punjab (PK), Government College Women University Sialkot, King Khalid University (SA), University of Gujrat (PK)

King Khalid University

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Openalex Percentile: Top 95%

Synthesis and biological activity

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Discovery of <i>bis</i> -chalcones and <i>bis</i> -pyrimidines as potential urease inhibitors: from synthesis to computational insights — Amina Sadiq, Mohamed I. A. Othman, et al. · Future Medicinal Chemistry (2025) | TGRS Research Map | TGRS