Upregulation of Nrf2 attenuates Angiostrongylus cantonensis-induced parasitic meningitis in mice
Our findings revealed the albendazole-Nrf2 activator co-treatment effectively suppressed excessive inflammation compared with the anthelmintics drug (albendazole) treatment alone, and Nrf2 activation might produce a synergistic effect in the inflammatory response of the brain in mice with angiostrongyliasis.
Authors
- Shih‐Chan Lai (ORCID: https://orcid.org/0000-0003-4230-4320)
- Shyun Chou (ORCID: https://orcid.org/0000-0001-6277-2581)
- Chih-Hao Chiu
- Chiung-Hung Hsu (ORCID: https://orcid.org/0000-0002-5377-0856)
- Yu‐Kang Chang (ORCID: https://orcid.org/0000-0002-2687-4801)
- Kemin Chen (ORCID: https://orcid.org/0000-0002-2778-3098)
- Chii-Wen Chou
- Cheng‐You Lu (ORCID: https://orcid.org/0000-0001-6807-3837)
- Wan‐Jing Chen (ORCID: https://orcid.org/0000-0003-0086-4231)
- Chun‐I Wang (ORCID: https://orcid.org/0000-0001-8332-0162)
- Kuan‐Yu Lin (ORCID: https://orcid.org/0000-0003-0559-3514)
- Chia-Chun Huang
Institutions
- National Chung Hsing University (TW)
- China Medical University (TW)
- Kuang Tien General Hospital (TW)
- Taichung Veterans General Hospital (TW)
- Tungs' Taichung MetroHarbor Hospital (TW)
- Cardinal Tien Hospital (TW)
- Kang-Ning Junior College of Medical Care and Management (TW)
- Central Taiwan University of Science and Technology (TW)
- Chung Shan Medical University (TW)
Publication Details
- Journal
- Parasites & Vectors
- Published
- 2025-04-03
- DOI
- https://doi.org/10.1186/s13071-025-06724-z
- Primary Topic
- Mollusks and Parasites Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00