Analysis of human brain RNA-seq data reveals combined effects of 4 types of RNA modifications and 18 types of programmed cell death on Alzheimer’s disease
This study uncovered that RNA modification-related PCD is of significance for AD progression and early prediction, providing insights from a new perspective for the study of disease mechanisms in AD.
Authors
- Maoyi Tian (ORCID: https://orcid.org/0000-0002-5660-8571)
- Qing Xia (ORCID: https://orcid.org/0000-0002-0506-9977)
- Lulu Liu (ORCID: https://orcid.org/0000-0001-9257-9512)
- Dayong Wang (ORCID: https://orcid.org/0000-0002-9672-3347)
- Ke Ye (ORCID: https://orcid.org/0000-0002-9593-9007)
- Xu Gao (ORCID: https://orcid.org/0000-0001-9040-4970)
- Xinyu Han (ORCID: https://orcid.org/0009-0003-2843-6025)
Institutions
- Harbin Medical University (CN)
- Heilongjiang Academy of Sciences (CN)
- Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine (CN)
- Education Department of Heilongjiang Province (CN)
- Heilongjiang University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-04-03
- DOI
- https://doi.org/10.1186/s12967-025-06324-6
- Citations
- 6
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 4.84
Funders
- Harbin Medical University
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Beijing University of Chinese Medicine
- Natural Science Foundation of Heilongjiang Province
- National Key Research and Development Program of China